After the surgery

Surgery will leave a scar in the form of healing. At the same time there are individuals conditions in which wound healing is significantly impeded (such disease is diabetes). Care of post-surgical or other wounds is important in the healing process, but not only. That is how quickly and with what effect will heal the wound depends on several factors, such as proper blood circulation and oxidation of newly emerging tissues.

The wounds are characterized by a lower level of oxygenation and blood flow than other parts of the skin, for this reason the healing process is slower. The natural impulse acting in the place of wound, injury or ulcers, which stimulates the body to begin the process of tissue regeneration, is the hypoxia. It is due to local hypoxia occurs to stimulate appropriate growth factors that initiate the wound healing process. These growth factors have increased activity only locally, at a wound site, for this reason, their effects are relatively weak. However, there is the possibility of allowing enhance their efficiency and thereby accelerate the healing of the wound while maintaining the aesthetic qualities of the large scar tissue.




Such a possibility is given by LOXYS, allowing you to create the conditions of high altitude, and thus lead to subtle tissue hypoxia. This allows you to stimulate your body to run the mechanisms of adaptation to altitude. Adaptation of the human body to the altitude has many features analogous to the process of wound healing. Both globally throughout the human body, as well as the site of the wound, comes to the increased activity of hypoxia inducible factor (HIF). Within the wound HIF activity reaches its maximum in the sixth hour, and then decreases. After about 24 hours the activity of hypoxia-inducible factor within the tissue reaches reconstructing output value. From this moment begins the healing slower while coming myofibroblasts (modified fibroblasts) begin to fill cavities tissue by collagen production. Arising in this way new tissue is poorly vascularized, has a different structure and is clearly distinguishable from the surrounding skin tissue. Being Human (short but intense) in terms of altitude allows you to keep the high activity of hypoxia-inducible factor. Thus, the process is exacerbated by new blood vessel formation in hypoxic particularly, in this case within the wound.




Vascular endothelial growth factor (VEGF), which is responsible for the formation of new blood vessels, together with the influence factor HIF stimulates the synthesis of nitric oxide. Higher levels of nitric oxide within the space-healing allows the relaxation of blood vessels and concomitant increase in the permeability of cell membranes. This produces local tissue inflammation mobilizing for greater differentiation (Jorge E. 2001). Simultaneous conditioning of new fibroblasts under hypoxic conditions can be achieved analogous conditions to those prevailing in the fetal condition when appropriate tissues are formed. Differentiated fibroblasts in such conditions give excellent cosmetic results (Kellar RS. 2009). This effect is possible due to said subtle hypoxia, so that within the emerging fibroblasts much more strongly affected by epidermal growth factor (EGF). This factor accelerates wound healing, improves the nutrition and hydration of the skin, stimulates creative divisions layer of the epidermis. At the higher concentrations, there is a smoothing of the skin and smoothing out wrinkles.

The process of wound healing with the use of stimulant effect of altitude climate. At the same time the human being in terms of lifting is a form of rehabilitation, a factor that gives a number of other positive health effects.